Endocrine Abstracts

Stimulation of insulin release by increased gut hormone levels after gastric bypass surgery, especially glucagonlike polypeptide-1(GLP-1), is considered to be the most important mechanism of action in diabetes remission. However, these beneficial effects can come at a price, namely the development of postprandial hyperinsulinaemic hypoglycaemia, more often called post bariatric hypoglycaemie (PBH). The exact pathophysiology of PBH is not known but GLP-1 plays an important role...

Background: Nutrition is essential in achieving maximal treatment success after bariatric surgery, and is simultaneously beneficial for avoiding long-term complications. Dietary protein could have an important role, because of its positive effects on preservation of muscle mass and induction of satiety in non-bariatric subjects. Therefore, we investigated the effects of dietary protein, assessed by amino acid composition, on satiety, hunger and gastrointestinal hormones after ...

Context: Roux-en-Y Gastric bypass (RYGB) is an effective way to induce sustainable weight loss. This operation can be complicated by late dumping, also known as postgastric bypass hyperinsulinemic hypoglycemia. Much is still unknown on its prevalence and its pathophysiology.Objective: To study the prevalence and the main driving mechanisms behind the occurrence of hypoglycemia after a mixed meal tolerance test (MMTT) in patients with primary RYGB. Design...